Molecular diversity of mitochondrial DNA in Iranian Azeri ethnicities vis-à-vis other Azeris in Asia

Document Type : Research Paper


1 Biotechnology Research Center, Tabriz University of Medical Sciences, P.O. Box 51666-14766, Tabriz, I.R. Iran.

2 Epidemiology Research Center, Aja University of Medical Sciences, P.O. Box 1411718541, Tehran, I.R. Iran.

3 Hematology and Oncology Research Center, Tabriz Univeristy of Medical Sciences, P.O. Box 51666-14766, Tabriz, I.R. Iran.

4 Department of Clinical Biochemistry, Shahid Beheshti University of Medical Sciences, P.O.Box: 1985717443, Tehran, I.R. Iran.


In order to investigate the molecular diversity of mtDNA in Azeri population, 133 Azeri subjects inhabiting
different regions of Azerbaijan (Iran) were selected. Blood samples were taken from these subjects for
mtDNA extraction. The extracted mtDNA samples were then studied by the PCR-RFLP method.
Fourteen haplogroups were characterized from which 82% were identified as European specific haplogroups.
The H haplogroup was the most frequent and 79 haplotypes were specified. In this study, the Iranian Azeri population was found to be a heterogenic population where all the specific haplogroups of Asians, Europeans and Africans were present in the studied population. Comparing the haplogroups of the present investigation with other populations indicated a very close similarity with other Iranian populations, but was different from haplogroups of other Asian populations who also speak the Azeri language.